An Autonomous Oscillation Times and Executes Centriole Biogenesis

The accurate timing and execution of organelle biogenesis is crucial for cell physiology. Centriole biogenesis is regulated by Polo-like kinase 4 (Plk4) and initiates in S-phase when a daughter centriole grows from the side of a pre-existing mother. Here, we show that a Plk4 oscillation at the base...

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Detalles Bibliográficos
Autores principales: Aydogan, Mustafa G., Steinacker, Thomas L., Mofatteh, Mohammad, Wilmott, Zachary M., Zhou, Felix Y., Gartenmann, Lisa, Wainman, Alan, Saurya, Saroj, Novak, Zsofia A., Wong, Siu-Shing, Goriely, Alain, Boemo, Michael A., Raff, Jordan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327525/
https://www.ncbi.nlm.nih.gov/pubmed/32531200
http://dx.doi.org/10.1016/j.cell.2020.05.018

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