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Multiple myeloma exploits Jagged1 and Jagged2 to promote intrinsic and bone marrow-dependent drug resistance
Multiple myeloma is still incurable due to an intrinsic aggressiveness or, more frequently, to the interactions of malignant plasma cells with the bone marrow (BM) microenvironment. Myeloma cells educate BM cells to support neoplastic cell growth, survival, acquisition of drug resistance resulting i...
Autores principales: | Colombo, Michela, Garavelli, Silvia, Mazzola, Mara, Platonova, Natalia, Giannandrea, Domenica, Colella, Raffaella, Apicella, Luana, Lancellotti, Marialuigia, Lesma, Elena, Ancona, Silvia, Palano, Maria Teresa, Barbieri, Marzia, Taiana, Elisa, Lazzari, Elisa, Basile, Andrea, Turrini, Mauro, Pistocchi, Anna, Neri, Antonino, Chiaramonte, Raffaella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327642/ https://www.ncbi.nlm.nih.gov/pubmed/31582544 http://dx.doi.org/10.3324/haematol.2019.221077 |
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