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Cytoplasmic, but not nuclear Nrf2 expression, is associated with inferior survival and relapse rate and response to platinum‐based chemotherapy in non‐small cell lung cancer
BACKGROUND: Several studies have previously indicated that nuclear factor erythroid 2‐related factor 2 (Nrf2) expression may promote tumor progression when the Keap1/Nrf2 pathway is activated, but few reports have demonstrated the role of cytoplasmic Nrf2 on tumorigenesis. METHODS: Immunohistochemis...
Autores principales: | Chen, Ming‐Jenn, Lin, Po‐Lin, Wang, Lee, Cheng, Ya‐Min, Chen, Chih‐Yi, Lee, Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327683/ https://www.ncbi.nlm.nih.gov/pubmed/32394538 http://dx.doi.org/10.1111/1759-7714.13479 |
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