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LncRNA HOTAIR enhances breast cancer radioresistance through facilitating HSPA1A expression via sequestering miR‐449b‐5p

BACKGROUND: Breast cancer (BRCA) is the leading cause of cancer‐related death in women worldwide. Pre‐ and postoperative radiotherapy play a pivotal role in BRCA treatment but its efficacy remains limited and plagued by the emergence of radiation resistance, which aggravates patient prognosis. The l...

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Detalles Bibliográficos
Autores principales: Zhang, Shuqin, Wang, Bin, Xiao, Huiwen, Dong, Jiali, Li, Yuan, Zhu, Changchun, Jin, Yuxiao, Li, Hang, Cui, Ming, Fan, Saijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327697/
https://www.ncbi.nlm.nih.gov/pubmed/32374522
http://dx.doi.org/10.1111/1759-7714.13450

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