Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes

In this paper, we present an occupational dataset to evaluate benzene exposure on the effective biomarkers of genetic damage, indicated as cytokinesis-block micronucleus (MN) frequency, hematotoxicity, indicated as white blood cells (WBC) counts, and molecular marker of telomere length (TL). And we...

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Autores principales: Ren, Jing-chao, Liu, Huan, Zhang, Guang-hui, Wang, Tongshuai, Li, Jingzhi, Dong, Tingting, Wu, Hantian, Xia, Zhao-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Medicine and Dentistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327812/
https://www.ncbi.nlm.nih.gov/pubmed/32637486
http://dx.doi.org/10.1016/j.dib.2020.105869
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author Ren, Jing-chao
Liu, Huan
Zhang, Guang-hui
Wang, Tongshuai
Li, Jingzhi
Dong, Tingting
Wu, Hantian
Xia, Zhao-lin
author_facet Ren, Jing-chao
Liu, Huan
Zhang, Guang-hui
Wang, Tongshuai
Li, Jingzhi
Dong, Tingting
Wu, Hantian
Xia, Zhao-lin
author_sort Ren, Jing-chao
collection PubMed
description In this paper, we present an occupational dataset to evaluate benzene exposure on the effective biomarkers of genetic damage, indicated as cytokinesis-block micronucleus (MN) frequency, hematotoxicity, indicated as white blood cells (WBC) counts, and molecular marker of telomere length (TL). And we further to eliminate the mechanism of benzene induced damage. Then evaluate the effects of sites polymorphism in environmental response genes, including 18 sites in metabolic and DNA repair genes, and the interaction between gene polymorphism and benzene exposure. This dataset is supplementary to the submitted research by [1] focused on the biomarkers TL, and a detailed description of the subjects sampling, biomarkers detection, data analysis and discussion are discussed in detail.
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spelling pubmed-73278122020-07-06 Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes Ren, Jing-chao Liu, Huan Zhang, Guang-hui Wang, Tongshuai Li, Jingzhi Dong, Tingting Wu, Hantian Xia, Zhao-lin Data Brief Medicine and Dentistry In this paper, we present an occupational dataset to evaluate benzene exposure on the effective biomarkers of genetic damage, indicated as cytokinesis-block micronucleus (MN) frequency, hematotoxicity, indicated as white blood cells (WBC) counts, and molecular marker of telomere length (TL). And we further to eliminate the mechanism of benzene induced damage. Then evaluate the effects of sites polymorphism in environmental response genes, including 18 sites in metabolic and DNA repair genes, and the interaction between gene polymorphism and benzene exposure. This dataset is supplementary to the submitted research by [1] focused on the biomarkers TL, and a detailed description of the subjects sampling, biomarkers detection, data analysis and discussion are discussed in detail. Elsevier 2020-06-18 /pmc/articles/PMC7327812/ /pubmed/32637486 http://dx.doi.org/10.1016/j.dib.2020.105869 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Medicine and Dentistry
Ren, Jing-chao
Liu, Huan
Zhang, Guang-hui
Wang, Tongshuai
Li, Jingzhi
Dong, Tingting
Wu, Hantian
Xia, Zhao-lin
Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes
title Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes
title_full Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes
title_fullStr Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes
title_full_unstemmed Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes
title_short Dataset on the effect of Benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and DNA repair genes
title_sort dataset on the effect of benzene exposure on genetic damage, hematotoxicity, telomere length and polymorphisms in metabolic and dna repair genes
topic Medicine and Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327812/
https://www.ncbi.nlm.nih.gov/pubmed/32637486
http://dx.doi.org/10.1016/j.dib.2020.105869
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