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Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii
The nosocomial Acinetobacter baumannii is one of the most opportunistic pathogens that resists almost a broad range of antibiotics. Some bacterial metal acquisition systems are introduced as potential virulence factors in pathogen-host interaction. Bacterial zinc uptake (Znu) systems are critical t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327815/ https://www.ncbi.nlm.nih.gov/pubmed/32637498 http://dx.doi.org/10.1016/j.dib.2020.105892 |
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author | Mobarak Qamsari, Maryam Rasooli, Iraj Darvish Alipour Astaneh, Shakiba |
author_facet | Mobarak Qamsari, Maryam Rasooli, Iraj Darvish Alipour Astaneh, Shakiba |
author_sort | Mobarak Qamsari, Maryam |
collection | PubMed |
description | The nosocomial Acinetobacter baumannii is one of the most opportunistic pathogens that resists almost a broad range of antibiotics. Some bacterial metal acquisition systems are introduced as potential virulence factors in pathogen-host interaction. Bacterial zinc uptake (Znu) systems are critical transporters that play a major role in the survival of the pathogen and the establishment of infections. In silico characterization of ZnuD shows that it is an outer membrane protein with high conservancy rates in most Acinetobacter baumannii strains. The in silico derived physicochemical properties, structural and conserved immunoinformatic prediction data among Acinetobacter baumannii strains confirm that ZnuD belongs to Ton B dependent siderophore receptor families and is considered as a potential vaccine candidate. A more detailed interpretation of the data presented in this article is provided in “Identification and immunogenic properties of recombinant ZnuD protein loops of Acinetobacter baumannii” [1]. |
format | Online Article Text |
id | pubmed-7327815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-73278152020-07-06 Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii Mobarak Qamsari, Maryam Rasooli, Iraj Darvish Alipour Astaneh, Shakiba Data Brief Immunology and Microbiology The nosocomial Acinetobacter baumannii is one of the most opportunistic pathogens that resists almost a broad range of antibiotics. Some bacterial metal acquisition systems are introduced as potential virulence factors in pathogen-host interaction. Bacterial zinc uptake (Znu) systems are critical transporters that play a major role in the survival of the pathogen and the establishment of infections. In silico characterization of ZnuD shows that it is an outer membrane protein with high conservancy rates in most Acinetobacter baumannii strains. The in silico derived physicochemical properties, structural and conserved immunoinformatic prediction data among Acinetobacter baumannii strains confirm that ZnuD belongs to Ton B dependent siderophore receptor families and is considered as a potential vaccine candidate. A more detailed interpretation of the data presented in this article is provided in “Identification and immunogenic properties of recombinant ZnuD protein loops of Acinetobacter baumannii” [1]. Elsevier 2020-06-20 /pmc/articles/PMC7327815/ /pubmed/32637498 http://dx.doi.org/10.1016/j.dib.2020.105892 Text en © 2020 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Immunology and Microbiology Mobarak Qamsari, Maryam Rasooli, Iraj Darvish Alipour Astaneh, Shakiba Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii |
title | Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii |
title_full | Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii |
title_fullStr | Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii |
title_full_unstemmed | Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii |
title_short | Data retrieved from in silico evaluation of vaccine potential of ZnuD protein in Acinetobacter baumannii |
title_sort | data retrieved from in silico evaluation of vaccine potential of znud protein in acinetobacter baumannii |
topic | Immunology and Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327815/ https://www.ncbi.nlm.nih.gov/pubmed/32637498 http://dx.doi.org/10.1016/j.dib.2020.105892 |
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