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Cardiac troponin and tropomyosin bind to F‐actin cooperatively, as revealed by fluorescence microscopy
In cardiac muscle, binding of troponin (Tn) and tropomyosin (Tpm) to filamentous (F)‐actin forms thin filaments capable of Ca(2+)‐dependent regulation of contraction. Tpm binds to F‐actin in a head‐to‐tail fashion, while Tn stabilizes these linkages. Valuable structural and functional information ha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327902/ https://www.ncbi.nlm.nih.gov/pubmed/32385956 http://dx.doi.org/10.1002/2211-5463.12876 |