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The impact of pre-existing HLA and red blood cell antibodies on transfusion support and engraftment in sickle cell disease after nonmyeloablative hematopoietic stem cell transplantation from HLA-matched sibling donors: A prospective, single-center, observational study

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is curative for patients with sickle cell disease (SCD). Prior to HSCT, patients with SCD commonly receive RBC transfusions with some becoming RBC or HLA alloimmunized. This alloimmunization may impact post-HSCT transfusion requirements and...

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Detalles Bibliográficos
Autores principales:	Nickel, Robert Sheppard, Flegel, Willy A., Adams, Sharon D., Hendrickson, Jeanne E., Liang, Hua, Tisdale, John F., Hsieh, Matthew M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327930/ https://www.ncbi.nlm.nih.gov/pubmed/32637902 http://dx.doi.org/10.1016/j.eclinm.2020.100432

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