Programmed switch in the mitochondrial degradation pathways during human retinal ganglion cell differentiation from stem cells is critical for RGC survival

Retinal ganglion cell (RGC) degeneration is the root cause for vision loss in glaucoma as well as in other forms of optic neuropathy. A variety of studies have implicated abnormal mitochondrial quality control (MQC) as contributing to RGC damage and degeneration in optic neuropathies. The ability to...

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Detalles Bibliográficos
Autores principales: Das, Arupratan, Bell, Claire M., Berlinicke, Cynthia A., Marsh-Armstrong, Nicholas, Zack, Donald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Articles from the Special Issue on Oxidative stress in retina and retinal pigment epithelium in health and disease; Edited by Vera Bonilha
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327961/
https://www.ncbi.nlm.nih.gov/pubmed/32473993
http://dx.doi.org/10.1016/j.redox.2020.101465

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