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End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

BACKGROUND: The molecular mechanisms underlying chronic kidney disease (CKD) transition to end-stage renal disease (ESRD) and CKD acceleration of cardiovascular and other tissue inflammations remain poorly determined. METHODS: We conducted a comprehensive data analyses on 7 microarray datasets in pe...

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Detalles Bibliográficos
Autores principales: Zhang, Ruijing, Saredy, Jason, Shao, Ying, Yao, Tian, Liu, Lu, Saaoud, Fatma, Yang, William Y., Sun, Yu, Johnson, Candice, Drummer, Charles, Fu, Hangfei, Lu, Yifan, Xu, Keman, Liu, Ming, Wang, Jirong, Cutler, Elizabeth, Yu, Daohai, Jiang, Xiaohua, Li, Yafeng, Li, Rongshan, Wang, Lihua, Choi, Eric T., Wang, Hong, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327976/
https://www.ncbi.nlm.nih.gov/pubmed/32179051
http://dx.doi.org/10.1016/j.redox.2020.101460

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