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The aryl hydrocarbon receptor as a target of environmental stressors – Implications for pollution mediated stress and inflammatory responses
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) 1A1 and CYP1A2, which are important enzymes in metabolism of xenobiotics. The AHR is activated upon binding of polycyclic...
Autores principales: | Vogel, Christoph F.A., Van Winkle, Laura S., Esser, Charlotte, Haarmann-Stemmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327980/ https://www.ncbi.nlm.nih.gov/pubmed/32354640 http://dx.doi.org/10.1016/j.redox.2020.101530 |
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