CircRNA_0001449 disturbs phosphatidylinositol homeostasis and AKT activity by enhancing Osbpl5 translation in transient cerebral ischemia

Phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3] is a phosphorylated derivative of phosphatidylinositol 4-phosphate [PI(4)P] and phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2], which recruit and activate AKT in the plasma membrane (PM) to promote cellular survival. ORP5 anchors at the endop...

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Detalles Bibliográficos
Autores principales: Shang, Fei-Fei, Luo, Li, Yan, Jianghong, Yu, Qiubo, Guo, Yongzheng, Wen, Yuchen, Min, Xiao-Li, Jiang, Ling, He, Xiang, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Articles from the Special Issue on Redox Signalling and Cardiovascular Disease; Edited by Christopher Kevil and Yabing Chen
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327991/
https://www.ncbi.nlm.nih.gov/pubmed/32086008
http://dx.doi.org/10.1016/j.redox.2020.101459

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