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Drosophila Sas-6, Ana2 and Sas-4 self-organise into macromolecular structures that can be used to probe centriole and centrosome assembly

Centriole assembly requires a small number of conserved proteins. The precise pathway of centriole assembly has been difficult to study, as the lack of any one of the core assembly proteins [Plk4, Ana2 (the homologue of mammalian STIL), Sas-6, Sas-4 (mammalian CPAP) or Asl (mammalian Cep152)] leads...

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Detalles Bibliográficos
Autores principales: Gartenmann, Lisa, Vicente, Catarina C., Wainman, Alan, Novak, Zsofi A., Sieber, Boris, Richens, Jennifer H., Raff, Jordan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328145/
https://www.ncbi.nlm.nih.gov/pubmed/32409564
http://dx.doi.org/10.1242/jcs.244574

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