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Drosophila Sas-6, Ana2 and Sas-4 self-organise into macromolecular structures that can be used to probe centriole and centrosome assembly
Centriole assembly requires a small number of conserved proteins. The precise pathway of centriole assembly has been difficult to study, as the lack of any one of the core assembly proteins [Plk4, Ana2 (the homologue of mammalian STIL), Sas-6, Sas-4 (mammalian CPAP) or Asl (mammalian Cep152)] leads...
Autores principales: | Gartenmann, Lisa, Vicente, Catarina C., Wainman, Alan, Novak, Zsofi A., Sieber, Boris, Richens, Jennifer H., Raff, Jordan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328145/ https://www.ncbi.nlm.nih.gov/pubmed/32409564 http://dx.doi.org/10.1242/jcs.244574 |
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