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Zebrafish models of skeletal dysplasia induced by cholesterol biosynthesis deficiency
Human disorders of the post-squalene cholesterol biosynthesis pathway frequently result in skeletal abnormalities, yet our understanding of the mechanisms involved is limited. In a forward-genetic approach, we have found that a late-onset skeletal mutant, named koliber(nu7), is the result of a cis-a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328163/ https://www.ncbi.nlm.nih.gov/pubmed/32430393 http://dx.doi.org/10.1242/dmm.042549 |