Highly efficient generation of sheep with a defined FecB(B) mutation via adenine base editing

Base editing has the potential to improve important economic traits in agriculture and can precisely convert single nucleotides in DNA or RNA sequences into minimal double-strand DNA breaks (DSB). Adenine base editors (ABE) have recently emerged as a base editing tool for the conversion of targeted...

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Detalles Bibliográficos
Autores principales: Zhou, Shiwei, Ding, Yige, Liu, Jiao, Liu, Yao, Zhao, Xiaoe, Li, Guanwei, Zhang, Chenguang, Li, Chao, Wang, Ying, Kalds, Peter, Gao, Yawei, Zong, Bo, Huang, Xiaoyu, Huang, Shuhong, Yu, Honghao, Kou, Qifang, Petersen, Bjoern, Huang, Xingxu, Wang, Xiaolong, Ma, Baohua, Chen, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328262/
https://www.ncbi.nlm.nih.gov/pubmed/32611306
http://dx.doi.org/10.1186/s12711-020-00554-6

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