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Histological transformation of lung adenocarcinoma to small cell lung cancer with mutant C797S conferring acquired resistance to osimertinib

Epidermal growth factor receptor (EGFR) gene-mutated non-small cell lung cancer may initially respond to EGFR tyrosine kinase inhibitors (TKIs), but may subsequently become resistant; however, the resistance mechanisms remain unclear. We report a rare case of acquired resistance to osimertinib assoc...

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Detalles Bibliográficos
Autores principales:	Ren, Xiaohui, Cai, Xinfeng, Li, Jing, Zhang, Xia, Yu, Jianfei, Song, Xin, Zhang, Henghui, Song, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328482/ https://www.ncbi.nlm.nih.gov/pubmed/32600081 http://dx.doi.org/10.1177/0300060520927918

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