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HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity

Chromatin modifiers play critical roles in epidermal development, but the functions of histone deacetylases in this context are poorly understood. The class I HDAC, HDAC3, is of particular interest because it plays divergent roles in different tissues by partnering with tissue-specific transcription...

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Detalles Bibliográficos
Autores principales: Szigety, Katherine M., Liu, Fang, Yuan, Chase Y., Moran, Deborah J., Horrell, Jeremy, Gochnauer, Heather R., Cohen, Ronald N., Katz, Jonathan P., Kaestner, Klaus H., Seykora, John T., Tobias, John W., Lazar, Mitchell A., Xu, Mingang, Millar, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328513/
https://www.ncbi.nlm.nih.gov/pubmed/32467224
http://dx.doi.org/10.1101/gad.333674.119