A central role for canonical PRC1 in shaping the 3D nuclear landscape

Polycomb group (PcG) proteins silence gene expression by chemically and physically modifying chromatin. A subset of PcG target loci are compacted and cluster in the nucleus; a conformation that is thought to contribute to gene silencing. However, how these interactions influence gross nuclear organi...

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Detalles Bibliográficos
Autores principales: Boyle, Shelagh, Flyamer, Ilya M., Williamson, Iain, Sengupta, Dipta, Bickmore, Wendy A., Illingworth, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328521/
https://www.ncbi.nlm.nih.gov/pubmed/32439634
http://dx.doi.org/10.1101/gad.336487.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328521/
https://www.ncbi.nlm.nih.gov/pubmed/32439634
http://dx.doi.org/10.1101/gad.336487.120

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