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Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()

We report a coronavirus disease 2019 (COVID-19) case with rheumatoid arthritis taking iguratimod. The patient who continued iguratimod therapy without dose reduction was treated with ciclesonide had an uneventful clinical course, but prolonged detection of severe acute respiratory syndrome coronavir...

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Autores principales: Baba, Hiroaki, Kanamori, Hajime, Oshima, Kengo, Seike, Issei, Niitsuma-Sugaya, Ikumi, Takei, Kentaro, Sato, Yukio, Tokuda, Koichi, Aoyagi, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328613/
https://www.ncbi.nlm.nih.gov/pubmed/32631736
http://dx.doi.org/10.1016/j.jiac.2020.06.022
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author Baba, Hiroaki
Kanamori, Hajime
Oshima, Kengo
Seike, Issei
Niitsuma-Sugaya, Ikumi
Takei, Kentaro
Sato, Yukio
Tokuda, Koichi
Aoyagi, Tetsuji
author_facet Baba, Hiroaki
Kanamori, Hajime
Oshima, Kengo
Seike, Issei
Niitsuma-Sugaya, Ikumi
Takei, Kentaro
Sato, Yukio
Tokuda, Koichi
Aoyagi, Tetsuji
author_sort Baba, Hiroaki
collection PubMed
description We report a coronavirus disease 2019 (COVID-19) case with rheumatoid arthritis taking iguratimod. The patient who continued iguratimod therapy without dose reduction was treated with ciclesonide had an uneventful clinical course, but prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was observed after resolution of symptoms. The effects of disease-modifying antirheumatic drugs (DMARDs) and ciclesonide on clinical course and viral shedding remain unknown and warrant further investigation.
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spelling pubmed-73286132020-07-01 Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide() Baba, Hiroaki Kanamori, Hajime Oshima, Kengo Seike, Issei Niitsuma-Sugaya, Ikumi Takei, Kentaro Sato, Yukio Tokuda, Koichi Aoyagi, Tetsuji J Infect Chemother Case Report We report a coronavirus disease 2019 (COVID-19) case with rheumatoid arthritis taking iguratimod. The patient who continued iguratimod therapy without dose reduction was treated with ciclesonide had an uneventful clinical course, but prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was observed after resolution of symptoms. The effects of disease-modifying antirheumatic drugs (DMARDs) and ciclesonide on clinical course and viral shedding remain unknown and warrant further investigation. Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2020-10 2020-07-01 /pmc/articles/PMC7328613/ /pubmed/32631736 http://dx.doi.org/10.1016/j.jiac.2020.06.022 Text en © 2020 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Baba, Hiroaki
Kanamori, Hajime
Oshima, Kengo
Seike, Issei
Niitsuma-Sugaya, Ikumi
Takei, Kentaro
Sato, Yukio
Tokuda, Koichi
Aoyagi, Tetsuji
Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()
title Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()
title_full Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()
title_fullStr Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()
title_full_unstemmed Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()
title_short Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()
title_sort prolonged presence of sars-cov-2 in a covid-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328613/
https://www.ncbi.nlm.nih.gov/pubmed/32631736
http://dx.doi.org/10.1016/j.jiac.2020.06.022
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