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High-glucose environment accelerates annulus fibrosus cell apoptosis by regulating endoplasmic reticulum stress

Diabetes mellitus (DM) is an important risk factor of intervertebral disc degeneration. However, how DM affects annulus fibrosus (AF) biology remains unclear. The present study was aimed to investigate the effects and mechanism of high glucose on AF cell biology. Rat AF cells were cultured in baseli...

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Detalles Bibliográficos
Autores principales: Pang, Lianglong, Yang, Keshi, Zhang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328627/
https://www.ncbi.nlm.nih.gov/pubmed/32515472
http://dx.doi.org/10.1042/BSR20200262