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A hypothesis on the role of the human immune system in covid-19
The COVID-19 pandemic has not spared any continent. The disease has affected more than 7,500,000 individuals globally and killed approximately 450,000 individuals. The disease is caused by a very small virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is an enveloped si...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328644/ https://www.ncbi.nlm.nih.gov/pubmed/32629204 http://dx.doi.org/10.1016/j.mehy.2020.110066 |
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author | Khashkhosha, Hind Khairi Elhadi, Muhammed |
author_facet | Khashkhosha, Hind Khairi Elhadi, Muhammed |
author_sort | Khashkhosha, Hind Khairi |
collection | PubMed |
description | The COVID-19 pandemic has not spared any continent. The disease has affected more than 7,500,000 individuals globally and killed approximately 450,000 individuals. The disease is caused by a very small virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is an enveloped single-stranded RNA virus with a spike-like structure on its envelope that can interact with the angiotensin-converting enzyme 2 (ACE2) receptor after cleavage. ACE2 receptors are present in the human lungs and other organs. SARS-CoV-2 is a new virus that belongs to the subgenus Sarbecovirus; viruses in this subgenus have spread widely in the previous years and caused outbreaks of severe acute respiratory syndromes. |
format | Online Article Text |
id | pubmed-7328644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73286442020-07-01 A hypothesis on the role of the human immune system in covid-19 Khashkhosha, Hind Khairi Elhadi, Muhammed Med Hypotheses Article The COVID-19 pandemic has not spared any continent. The disease has affected more than 7,500,000 individuals globally and killed approximately 450,000 individuals. The disease is caused by a very small virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is an enveloped single-stranded RNA virus with a spike-like structure on its envelope that can interact with the angiotensin-converting enzyme 2 (ACE2) receptor after cleavage. ACE2 receptors are present in the human lungs and other organs. SARS-CoV-2 is a new virus that belongs to the subgenus Sarbecovirus; viruses in this subgenus have spread widely in the previous years and caused outbreaks of severe acute respiratory syndromes. Elsevier Ltd. 2020-10 2020-07-01 /pmc/articles/PMC7328644/ /pubmed/32629204 http://dx.doi.org/10.1016/j.mehy.2020.110066 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Khashkhosha, Hind Khairi Elhadi, Muhammed A hypothesis on the role of the human immune system in covid-19 |
title | A hypothesis on the role of the human immune system in covid-19 |
title_full | A hypothesis on the role of the human immune system in covid-19 |
title_fullStr | A hypothesis on the role of the human immune system in covid-19 |
title_full_unstemmed | A hypothesis on the role of the human immune system in covid-19 |
title_short | A hypothesis on the role of the human immune system in covid-19 |
title_sort | hypothesis on the role of the human immune system in covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328644/ https://www.ncbi.nlm.nih.gov/pubmed/32629204 http://dx.doi.org/10.1016/j.mehy.2020.110066 |
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