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Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage
The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of the chromatin not only affects the probability of DNA to undergo damage but also DNA repair. DNA damage can result in genetic alterations and subsequent development of cancer and o...
Autores principales: | Ortega, Pedro, García-Pichardo, Desiré, San Martin-Alonso, Marta, Rondón, Ana G., Gómez-González, Belén, Aguilera, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328676/ https://www.ncbi.nlm.nih.gov/pubmed/32656258 http://dx.doi.org/10.15698/mic2020.07.723 |
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