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Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China

China has the highest number of hepatitis B and C cases globally. Despite remarkable achievements, China faces daunting challenges in achieving international targets for hepatitis elimination. As part of a large-scale project assessing China’s progress in achieving health-related Sustainable Develop...

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Autores principales: Chen, Shu, Mao, Wenhui, Guo, Lei, Zhang, Jiahui, Tang, Shenglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328743/
https://www.ncbi.nlm.nih.gov/pubmed/32605935
http://dx.doi.org/10.1136/bmjgh-2020-002306
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author Chen, Shu
Mao, Wenhui
Guo, Lei
Zhang, Jiahui
Tang, Shenglan
author_facet Chen, Shu
Mao, Wenhui
Guo, Lei
Zhang, Jiahui
Tang, Shenglan
author_sort Chen, Shu
collection PubMed
description China has the highest number of hepatitis B and C cases globally. Despite remarkable achievements, China faces daunting challenges in achieving international targets for hepatitis elimination. As part of a large-scale project assessing China’s progress in achieving health-related Sustainable Development Goals using quantitative, qualitative data and mathematical modelling, this paper summarises the achievements, gaps and challenges, and proposes options for actions for hepatitis B and C control. China has made substantial progress in controlling chronic viral hepatitis. The four most successful strategies have been: (1) hepatitis B virus childhood immunisation; (2) prevention of mother-to-child transmission; (3) full coverage of nucleic acid amplification testing in blood stations and (4) effective financing strategies to support treatment. However, the total number of deaths due to hepatitis B and C is estimated to increase from 434 724 in 2017 to 527 829 in 2030 if there is no implementation of tailored interventions. Many health system barriers, including a fragmented governance system, insufficient funding, inadequate service coverage, unstandardised treatment and flawed information systems, have compromised the effective control of hepatitis B and C in China. We suggest five strategic priority actions to help eliminate hepatitis B and C in China: (1) restructure the viral hepatitis control governance system; (2) optimise health resource allocation and improve funding efficiency; (3) improve access to and the quality of the health benefits package, especially for high-risk groups; (4) strengthen information systems to obtain high-quality hepatitis epidemiological data; (5) increase investment in viral hepatitis research and development.
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spelling pubmed-73287432020-07-02 Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China Chen, Shu Mao, Wenhui Guo, Lei Zhang, Jiahui Tang, Shenglan BMJ Glob Health Analysis China has the highest number of hepatitis B and C cases globally. Despite remarkable achievements, China faces daunting challenges in achieving international targets for hepatitis elimination. As part of a large-scale project assessing China’s progress in achieving health-related Sustainable Development Goals using quantitative, qualitative data and mathematical modelling, this paper summarises the achievements, gaps and challenges, and proposes options for actions for hepatitis B and C control. China has made substantial progress in controlling chronic viral hepatitis. The four most successful strategies have been: (1) hepatitis B virus childhood immunisation; (2) prevention of mother-to-child transmission; (3) full coverage of nucleic acid amplification testing in blood stations and (4) effective financing strategies to support treatment. However, the total number of deaths due to hepatitis B and C is estimated to increase from 434 724 in 2017 to 527 829 in 2030 if there is no implementation of tailored interventions. Many health system barriers, including a fragmented governance system, insufficient funding, inadequate service coverage, unstandardised treatment and flawed information systems, have compromised the effective control of hepatitis B and C in China. We suggest five strategic priority actions to help eliminate hepatitis B and C in China: (1) restructure the viral hepatitis control governance system; (2) optimise health resource allocation and improve funding efficiency; (3) improve access to and the quality of the health benefits package, especially for high-risk groups; (4) strengthen information systems to obtain high-quality hepatitis epidemiological data; (5) increase investment in viral hepatitis research and development. BMJ Publishing Group 2020-06-30 /pmc/articles/PMC7328743/ /pubmed/32605935 http://dx.doi.org/10.1136/bmjgh-2020-002306 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Analysis
Chen, Shu
Mao, Wenhui
Guo, Lei
Zhang, Jiahui
Tang, Shenglan
Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China
title Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China
title_full Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China
title_fullStr Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China
title_full_unstemmed Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China
title_short Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China
title_sort combating hepatitis b and c by 2030: achievements, gaps, and options for actions in china
topic Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328743/
https://www.ncbi.nlm.nih.gov/pubmed/32605935
http://dx.doi.org/10.1136/bmjgh-2020-002306
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