Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report

Hydroxyurea is an oral medication associated with painful, nonhealing ulcers, for which there is no effective treatment but permanent discontinuation of hydroxyurea. The authors present a case of leg ulcers that likely occurred as a result of hydroxyurea use in a patient with essential thrombocythem...

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Detalles Bibliográficos
Autores principales: Zhao, Qiannan, Ma, Yuanyuan, Lu, Yuquan, Chai, Yuan, Zhou, Yuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Features: Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328864/
https://www.ncbi.nlm.nih.gov/pubmed/31764145
http://dx.doi.org/10.1097/01.ASW.0000604176.47082.60
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author Zhao, Qiannan
Ma, Yuanyuan
Lu, Yuquan
Chai, Yuan
Zhou, Yuemin
author_facet Zhao, Qiannan
Ma, Yuanyuan
Lu, Yuquan
Chai, Yuan
Zhou, Yuemin
author_sort Zhao, Qiannan
collection PubMed
description Hydroxyurea is an oral medication associated with painful, nonhealing ulcers, for which there is no effective treatment but permanent discontinuation of hydroxyurea. The authors present a case of leg ulcers that likely occurred as a result of hydroxyurea use in a patient with essential thrombocythemia. Topical treatment with allogeneic platelet-rich plasma and artificial dermis completely healed the leg ulcers without hydroxyurea cessation.
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spelling pubmed-73288642020-07-13 Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report Zhao, Qiannan Ma, Yuanyuan Lu, Yuquan Chai, Yuan Zhou, Yuemin Adv Skin Wound Care Features: Case Report Hydroxyurea is an oral medication associated with painful, nonhealing ulcers, for which there is no effective treatment but permanent discontinuation of hydroxyurea. The authors present a case of leg ulcers that likely occurred as a result of hydroxyurea use in a patient with essential thrombocythemia. Topical treatment with allogeneic platelet-rich plasma and artificial dermis completely healed the leg ulcers without hydroxyurea cessation. Lippincott Williams & Wilkins 2019-12 2019-11-25 /pmc/articles/PMC7328864/ /pubmed/31764145 http://dx.doi.org/10.1097/01.ASW.0000604176.47082.60 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Features: Case Report
Zhao, Qiannan
Ma, Yuanyuan
Lu, Yuquan
Chai, Yuan
Zhou, Yuemin
Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report
title Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report
title_full Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report
title_fullStr Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report
title_full_unstemmed Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report
title_short Successful Treatment of Chronic Lower Extremity Ulcers with Allogeneic Platelet-Rich Plasma and Artificial Dermis: A Case Report
title_sort successful treatment of chronic lower extremity ulcers with allogeneic platelet-rich plasma and artificial dermis: a case report
topic Features: Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328864/
https://www.ncbi.nlm.nih.gov/pubmed/31764145
http://dx.doi.org/10.1097/01.ASW.0000604176.47082.60
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