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Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review

RATIONALE: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research evidence showed that it was derived from natural epithelial tissue. On imaging, this tumor ma...

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Autores principales: Le, Huu Y, Pham, Dinh Phuc, Nguyen, Khac Tuyen, Hoang, Van Ai, Trinh, The Son, Do, Quyet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329001/
https://www.ncbi.nlm.nih.gov/pubmed/32590790
http://dx.doi.org/10.1097/MD.0000000000020869
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author Le, Huu Y
Pham, Dinh Phuc
Nguyen, Khac Tuyen
Hoang, Van Ai
Trinh, The Son
Do, Quyet
author_facet Le, Huu Y
Pham, Dinh Phuc
Nguyen, Khac Tuyen
Hoang, Van Ai
Trinh, The Son
Do, Quyet
author_sort Le, Huu Y
collection PubMed
description RATIONALE: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research evidence showed that it was derived from natural epithelial tissue. On imaging, this tumor may be found as a solitary well-circumscribed lung parenchymal lesion, and is often located in juxtapleural or juxtafissural positions. On histopathology, it consists of cuboidal surface cells and stromal round cells, both of which are positive for thyroid transcription factor-1. Here we report a case of a young PSP male patient and review the relevant literature in order to improve our understanding of this disease. PATIENT CONCERNS: An 18-year-old man was referred to our hospital after accidentally finding a lesion on chest X-ray. Contrast-enhanced computed tomography showed a soft tissue mass with homogeneous enhancement in the left lower lobe posterior segment. DIAGNOSES: The diagnosis of PSPs was confirmed by histopathological examination. INTERVENTIONS AND OUTCOMES: The patient underwent a thoracoscopic wedge resection and was followed-up after that. One month later, he had good performance status with no recurrent tumors. LESSONS: PSP in a young man is really uncommon, and is confused with malignant tumors. A histopathological examination is considered as the diagnostic gold standard for this uncommon tumor. Surgery is the main treatment.
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spelling pubmed-73290012020-07-09 Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review Le, Huu Y Pham, Dinh Phuc Nguyen, Khac Tuyen Hoang, Van Ai Trinh, The Son Do, Quyet Medicine (Baltimore) 6700 RATIONALE: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research evidence showed that it was derived from natural epithelial tissue. On imaging, this tumor may be found as a solitary well-circumscribed lung parenchymal lesion, and is often located in juxtapleural or juxtafissural positions. On histopathology, it consists of cuboidal surface cells and stromal round cells, both of which are positive for thyroid transcription factor-1. Here we report a case of a young PSP male patient and review the relevant literature in order to improve our understanding of this disease. PATIENT CONCERNS: An 18-year-old man was referred to our hospital after accidentally finding a lesion on chest X-ray. Contrast-enhanced computed tomography showed a soft tissue mass with homogeneous enhancement in the left lower lobe posterior segment. DIAGNOSES: The diagnosis of PSPs was confirmed by histopathological examination. INTERVENTIONS AND OUTCOMES: The patient underwent a thoracoscopic wedge resection and was followed-up after that. One month later, he had good performance status with no recurrent tumors. LESSONS: PSP in a young man is really uncommon, and is confused with malignant tumors. A histopathological examination is considered as the diagnostic gold standard for this uncommon tumor. Surgery is the main treatment. Wolters Kluwer Health 2020-06-26 /pmc/articles/PMC7329001/ /pubmed/32590790 http://dx.doi.org/10.1097/MD.0000000000020869 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6700
Le, Huu Y
Pham, Dinh Phuc
Nguyen, Khac Tuyen
Hoang, Van Ai
Trinh, The Son
Do, Quyet
Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review
title Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review
title_full Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review
title_fullStr Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review
title_full_unstemmed Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review
title_short Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review
title_sort pulmonary sclerosing pneumocytoma in an 18-year-old male patient: a case report and literature review
topic 6700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329001/
https://www.ncbi.nlm.nih.gov/pubmed/32590790
http://dx.doi.org/10.1097/MD.0000000000020869
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