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Virus Factories

Viral factories are intracellular compartments of the host cell that contain viral replication organelles and necessary elements for assembly and maturation of new infectious viral particles. In this article we revise the methods used to study viral factories and the current knowledge on the structu...

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Detalles Bibliográficos
Autores principales: Fernández de Castro, Isabel, Tenorio, Raquel, Risco, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329290/
http://dx.doi.org/10.1016/B978-0-12-814515-9.00001-1
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author Fernández de Castro, Isabel
Tenorio, Raquel
Risco, Cristina
author_facet Fernández de Castro, Isabel
Tenorio, Raquel
Risco, Cristina
author_sort Fernández de Castro, Isabel
collection PubMed
description Viral factories are intracellular compartments of the host cell that contain viral replication organelles and necessary elements for assembly and maturation of new infectious viral particles. In this article we revise the methods used to study viral factories and the current knowledge on the structure, functions and biogenesis of these structures. We also describe some of the most emblematic examples of viral factories characterized so far. Finally, we describe how the identification of mechanisms involved in the biogenesis and functional architecture of viral factories will provide new means for antiviral intervention.
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spelling pubmed-73292902020-07-02 Virus Factories Fernández de Castro, Isabel Tenorio, Raquel Risco, Cristina Encyclopedia of Virology Article Viral factories are intracellular compartments of the host cell that contain viral replication organelles and necessary elements for assembly and maturation of new infectious viral particles. In this article we revise the methods used to study viral factories and the current knowledge on the structure, functions and biogenesis of these structures. We also describe some of the most emblematic examples of viral factories characterized so far. Finally, we describe how the identification of mechanisms involved in the biogenesis and functional architecture of viral factories will provide new means for antiviral intervention. 2021 2021-03-01 /pmc/articles/PMC7329290/ http://dx.doi.org/10.1016/B978-0-12-814515-9.00001-1 Text en Copyright © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Fernández de Castro, Isabel
Tenorio, Raquel
Risco, Cristina
Virus Factories
title Virus Factories
title_full Virus Factories
title_fullStr Virus Factories
title_full_unstemmed Virus Factories
title_short Virus Factories
title_sort virus factories
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329290/
http://dx.doi.org/10.1016/B978-0-12-814515-9.00001-1
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