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Virus Factories
Viral factories are intracellular compartments of the host cell that contain viral replication organelles and necessary elements for assembly and maturation of new infectious viral particles. In this article we revise the methods used to study viral factories and the current knowledge on the structu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329290/ http://dx.doi.org/10.1016/B978-0-12-814515-9.00001-1 |
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author | Fernández de Castro, Isabel Tenorio, Raquel Risco, Cristina |
author_facet | Fernández de Castro, Isabel Tenorio, Raquel Risco, Cristina |
author_sort | Fernández de Castro, Isabel |
collection | PubMed |
description | Viral factories are intracellular compartments of the host cell that contain viral replication organelles and necessary elements for assembly and maturation of new infectious viral particles. In this article we revise the methods used to study viral factories and the current knowledge on the structure, functions and biogenesis of these structures. We also describe some of the most emblematic examples of viral factories characterized so far. Finally, we describe how the identification of mechanisms involved in the biogenesis and functional architecture of viral factories will provide new means for antiviral intervention. |
format | Online Article Text |
id | pubmed-7329290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
record_format | MEDLINE/PubMed |
spelling | pubmed-73292902020-07-02 Virus Factories Fernández de Castro, Isabel Tenorio, Raquel Risco, Cristina Encyclopedia of Virology Article Viral factories are intracellular compartments of the host cell that contain viral replication organelles and necessary elements for assembly and maturation of new infectious viral particles. In this article we revise the methods used to study viral factories and the current knowledge on the structure, functions and biogenesis of these structures. We also describe some of the most emblematic examples of viral factories characterized so far. Finally, we describe how the identification of mechanisms involved in the biogenesis and functional architecture of viral factories will provide new means for antiviral intervention. 2021 2021-03-01 /pmc/articles/PMC7329290/ http://dx.doi.org/10.1016/B978-0-12-814515-9.00001-1 Text en Copyright © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Fernández de Castro, Isabel Tenorio, Raquel Risco, Cristina Virus Factories |
title | Virus Factories |
title_full | Virus Factories |
title_fullStr | Virus Factories |
title_full_unstemmed | Virus Factories |
title_short | Virus Factories |
title_sort | virus factories |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329290/ http://dx.doi.org/10.1016/B978-0-12-814515-9.00001-1 |
work_keys_str_mv | AT fernandezdecastroisabel virusfactories AT tenorioraquel virusfactories AT riscocristina virusfactories |