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Investigating the importance of individual mitochondrial genotype in susceptibility to drug-induced toxicity

The mitochondrion is an essential organelle responsible for generating cellular energy. Additionally, mitochondria are a source of inter-individual variation as they contain their own genome. Evidence has revealed that mitochondrial DNA (mtDNA) variation can confer differences in mitochondrial funct...

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Detalles Bibliográficos
Autores principales:	Penman, Sophie L., Carter, Alice S., Chadwick, Amy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329340/ https://www.ncbi.nlm.nih.gov/pubmed/32453388 http://dx.doi.org/10.1042/BST20190233

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