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Comparative RNA-Seq transcriptome analyses reveal dynamic time-dependent effects of (56)Fe, (16)O, and (28)Si irradiation on the induction of murine hepatocellular carcinoma
BACKGROUND: One of the health risks posed to astronauts during deep space flights is exposure to high charge, high-energy (HZE) ions (Z > 13), which can lead to the induction of hepatocellular carcinoma (HCC). However, little is known on the molecular mechanisms of HZE irradiation-induced HCC. RE...
Autores principales: | Nia, Anna M., Khanipov, Kamil, Barnette, Brooke L., Ullrich, Robert L., Golovko, George, Emmett, Mark R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329445/ https://www.ncbi.nlm.nih.gov/pubmed/32611366 http://dx.doi.org/10.1186/s12864-020-06869-4 |
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