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Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration
BACKGROUND: Studies on tumor-secreted microRNAs point to a functional role of these in cellular communication and reprogramming of the tumor microenvironment. Uptake of tumor-secreted microRNAs by neighboring cells may result in the silencing of mRNA targets and, in turn, modulation of the transcrip...
Autores principales: | Terkelsen, Thilde, Russo, Francesco, Gromov, Pavel, Haakensen, Vilde Drageset, Brunak, Søren, Gromova, Irina, Krogh, Anders, Papaleo, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329449/ https://www.ncbi.nlm.nih.gov/pubmed/32605588 http://dx.doi.org/10.1186/s13058-020-01295-6 |
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