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A systematic review of the role of eculizumab in systemic lupus erythematosus-associated thrombotic microangiopathy
BACKGROUND: Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated pathways including the complement system. Complete r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329551/ https://www.ncbi.nlm.nih.gov/pubmed/32605540 http://dx.doi.org/10.1186/s12882-020-01888-5 |