Cargando…
Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation
Nurr1, a transcription factor belonging to the orphan nuclear receptor, has an essential role in the generation and maintenance of dopaminergic neurons and is important in the pathogenesis of Parkinson’ disease (PD). In addition, Nurr1 has a non-neuronal function, and it is especially well known tha...
Autores principales: | Oh, Mihee, Kim, Sun Young, Gil, Jung-Eun, Byun, Jeong-Su, Cha, Dong-Wook, Ku, Bonsu, Lee, Woonghee, Kim, Won-Kon, Oh, Kyoung-Jin, Lee, Eun-Woo, Bae, Kwang-Hee, Lee, Sang Chul, Han, Baek-Soo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329810/ https://www.ncbi.nlm.nih.gov/pubmed/32612143 http://dx.doi.org/10.1038/s41598-020-67549-7 |
Ejemplares similares
-
Dysregulation of RasGRP1 in rheumatoid arthritis and modulation of RasGRP3 as a biomarker of TNFα inhibitors
por: Golinski, Marie-Laure, et al.
Publicado: (2015) -
RasGRP1, but Not RasGRP3, Is Required for Efficient Thymic β-Selection and ERK Activation Downstream of CXCR4
por: Golec, Dominic P., et al.
Publicado: (2013) -
Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1
por: Iwig, Jeffrey S, et al.
Publicado: (2013) -
Function of RasGRP3 in the formation and progression of human breast cancer
por: Nagy, Zsuzsanna, et al.
Publicado: (2014) -
RasGRP2 Structure, Function and Genetic Variants in Platelet Pathophysiology
por: Canault, Matthias, et al.
Publicado: (2020)