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Conservation and divergence in NaChBac and Na(V)1.7 pharmacology reveals novel drug interaction mechanisms
Voltage-gated Na(+) (Na(V)) channels regulate homeostasis in bacteria and control membrane electrical excitability in mammals. Compared to their mammalian counterparts, bacterial Na(V) channels possess a simpler, fourfold symmetric structure and have facilitated studies of the structural basis of ch...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329812/ https://www.ncbi.nlm.nih.gov/pubmed/32612253 http://dx.doi.org/10.1038/s41598-020-67761-5 |