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Association study based on topological constraints of protein–protein interaction networks
The non-random interaction pattern of a protein–protein interaction network (PIN) is biologically informative, but its potentials have not been fully utilized in omics studies. Here, we propose a network-permutation-based association study (NetPAS) method that gauges the observed interactions betwee...
Autores principales: | Guo, Hao-Bo, Qin, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329836/ https://www.ncbi.nlm.nih.gov/pubmed/32612246 http://dx.doi.org/10.1038/s41598-020-67875-w |
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