NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice

Amyloid fibrils result from the aggregation of host cell-encoded proteins, many giving rise to specific human illnesses such as Alzheimer’s disease. Here we show that the major virulence factor of Rift Valley fever virus, the protein NSs, forms filamentous structures in the brain of mice and affects...

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Detalles Bibliográficos
Autores principales: Léger, Psylvia, Nachman, Eliana, Richter, Karsten, Tamietti, Carole, Koch, Jana, Burk, Robin, Kummer, Susann, Xin, Qilin, Stanifer, Megan, Bouloy, Michèle, Boulant, Steeve, Kräusslich, Hans-Georg, Montagutelli, Xavier, Flamand, Marie, Nussbaum-Krammer, Carmen, Lozach, Pierre-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329897/
https://www.ncbi.nlm.nih.gov/pubmed/32612175
http://dx.doi.org/10.1038/s41467-020-17101-y

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