How Biofilm Growth Affects Candida-Host Interactions

Candida spp. proliferate as surface-associated biofilms in a variety of clinical niches. These biofilms can be extremely difficult to eradicate in healthcare settings. Cells within biofilm communities grow as aggregates and produce a protective extracellular matrix, properties that impact the abilit...

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Detalles Bibliográficos
Autores principales: Eix, Emily F., Nett, Jeniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329980/
https://www.ncbi.nlm.nih.gov/pubmed/32670252
http://dx.doi.org/10.3389/fmicb.2020.01437
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author Eix, Emily F.
Nett, Jeniel E.
author_facet Eix, Emily F.
Nett, Jeniel E.
author_sort Eix, Emily F.
collection PubMed
description Candida spp. proliferate as surface-associated biofilms in a variety of clinical niches. These biofilms can be extremely difficult to eradicate in healthcare settings. Cells within biofilm communities grow as aggregates and produce a protective extracellular matrix, properties that impact the ability of the host to respond to infection. Cells that disperse from biofilms display a phenotype of enhanced pathogenicity. In this review, we highlight host-biofilm interactions for Candida, focusing on how biofilm formation influences innate immune responses.
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spelling pubmed-73299802020-07-14 How Biofilm Growth Affects Candida-Host Interactions Eix, Emily F. Nett, Jeniel E. Front Microbiol Microbiology Candida spp. proliferate as surface-associated biofilms in a variety of clinical niches. These biofilms can be extremely difficult to eradicate in healthcare settings. Cells within biofilm communities grow as aggregates and produce a protective extracellular matrix, properties that impact the ability of the host to respond to infection. Cells that disperse from biofilms display a phenotype of enhanced pathogenicity. In this review, we highlight host-biofilm interactions for Candida, focusing on how biofilm formation influences innate immune responses. Frontiers Media S.A. 2020-06-25 /pmc/articles/PMC7329980/ /pubmed/32670252 http://dx.doi.org/10.3389/fmicb.2020.01437 Text en Copyright © 2020 Eix and Nett. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Eix, Emily F.
Nett, Jeniel E.
How Biofilm Growth Affects Candida-Host Interactions
title How Biofilm Growth Affects Candida-Host Interactions
title_full How Biofilm Growth Affects Candida-Host Interactions
title_fullStr How Biofilm Growth Affects Candida-Host Interactions
title_full_unstemmed How Biofilm Growth Affects Candida-Host Interactions
title_short How Biofilm Growth Affects Candida-Host Interactions
title_sort how biofilm growth affects candida-host interactions
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329980/
https://www.ncbi.nlm.nih.gov/pubmed/32670252
http://dx.doi.org/10.3389/fmicb.2020.01437
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