Novel candidate drugs in anti-tumor necrosis factor refractory Crohn’s diseases: in silico study for drug repositioning

Biologicals like anti-tumor necrosis factor (TNF) therapy for Crohn’s disease (CD) are safe and effective but there is a significant rate of primary and secondary nonresponse in the patients. In this study, we applied a computational approach to discover novel drug therapies for anti-TNF refractory...

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Detalles Bibliográficos
Autores principales: Kwak, Min Seob, Lee, Hun Hee, Cha, Jae Myung, Shin, Hyun Phil, Jeon, Jung Won, Yoon, Jin Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330029/
https://www.ncbi.nlm.nih.gov/pubmed/32612148
http://dx.doi.org/10.1038/s41598-020-67801-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330029/
https://www.ncbi.nlm.nih.gov/pubmed/32612148
http://dx.doi.org/10.1038/s41598-020-67801-0

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