Molecular dissection of CRC primary tumors and their matched liver metastases reveals critical role of immune microenvironment, EMT and angiogenesis in cancer metastasis

Metastasis is the primary cause of cancer mortality. The primary tumors of colorectal cancer (CRC) often metastasize to the liver. In this study, we have collected 122 samples from 45 CRC patients. Among them, 32 patients have primary tumors, adjacent normal tissues, and matched liver metastases. Th...

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Detalles Bibliográficos
Autores principales: Liu, Jiangang, Cho, Yong Beom, Hong, Hye Kyung, Wu, Song, Ebert, Philip J., Bray, Steven M., Wong, Swee Seong, Ting, Jason C., Calley, John N., Whittington, Catherine F., Bhagwat, Shripad V., Reinhard, Christoph, Wild, Robert, Nam, Do-Hyun, Aggarwal, Amit, Lee, Woo Yong, Peng, Sheng-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330040/
https://www.ncbi.nlm.nih.gov/pubmed/32612211
http://dx.doi.org/10.1038/s41598-020-67842-5

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