Cargando…
SUMOylation in α-Synuclein Homeostasis and Pathology
The accumulation and aggregation of α-synuclein are central to Parkinson’s disease (PD), yet the molecular mechanisms responsible for these events are not fully understood. Post-translational modifications of α-synuclein regulate several of its properties, including degradation, interaction with pro...
Autores principales: | Savyon, Mor, Engelender, Simone |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330056/ https://www.ncbi.nlm.nih.gov/pubmed/32670048 http://dx.doi.org/10.3389/fnagi.2020.00167 |
Ejemplares similares
-
SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine
por: Zhu, Lin-nan, et al.
Publicado: (2018) -
Sumoylation Protects Against β-Synuclein Toxicity in Yeast
por: Popova, Blagovesta, et al.
Publicado: (2018) -
Sumoylation inhibits α-synuclein aggregation and toxicity
por: Krumova, Petranka, et al.
Publicado: (2011) -
Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation
por: Kunadt, Marcel, et al.
Publicado: (2015) -
Effect of L-DOPA/Benserazide on Propagation of Pathological α-Synuclein
por: Shimozawa, Aki, et al.
Publicado: (2019)