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Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy

Photoreceptor cell death and inflammation are known to occur progressively in retinal degenerative diseases such as age-related macular degeneration (AMD). However, the molecular mechanisms underlying these biological processes are largely unknown. Extracellular vesicles (EV) are essential mediators...

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Detalles Bibliográficos
Autores principales: Wooff, Yvette, Cioanca, Adrian V., Chu-Tan, Joshua A., Aggio-Bruce, Riemke, Schumann, Ulrike, Natoli, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330137/
https://www.ncbi.nlm.nih.gov/pubmed/32670023
http://dx.doi.org/10.3389/fncel.2020.00160