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Frequency of MET exon 14 skipping mutations in non-small cell lung cancer according to technical approach in routine diagnosis: results from a real-life cohort of 2,369 patients

BACKGROUND: Mesenchymal epithelial transition receptor (MET) alterations, including MET exon 14 skipping mutation, are oncogenic in non-small cell lung cancer (NSCLC) and may confer sensitivity to targeted therapy. Given the rarity and the diversity of exon 14 skipping mutations, diagnosis may be ch...

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Detalles Bibliográficos
Autores principales: Champagnac, Anne, Bringuier, Pierre-Paul, Barritault, Marc, Isaac, Sylvie, Watkin, Emmanuel, Forest, Fabien, Maury, Jean-Michel, Girard, Nicolas, Brevet, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330338/
https://www.ncbi.nlm.nih.gov/pubmed/32642122
http://dx.doi.org/10.21037/jtd.2020.04.21