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Handling multi-mapped reads in RNA-seq

Many eukaryotic genomes harbour large numbers of duplicated sequences, of diverse biotypes, resulting from several mechanisms including recombination, whole genome duplication and retro-transposition. Such repeated sequences complicate gene/transcript quantification during RNA-seq analysis due to re...

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Detalles Bibliográficos
Autores principales:	Deschamps-Francoeur, Gabrielle, Simoneau, Joël, Scott, Michelle S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330433/ https://www.ncbi.nlm.nih.gov/pubmed/32637053 http://dx.doi.org/10.1016/j.csbj.2020.06.014

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