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Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient

We followed–up a mild COVID-19 patient for 91 days and serially monitored his serum antibodies to four SARS-CoV-2 related antigens (NP, RBD, S1 and ECD) and neutralization activities. Our data revealed a profile of serial antibody responses during the progress and a quick decline of neutralization a...

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Detalles Bibliográficos
Autores principales: Yin, Shengxia, Tong, Xin, Huang, Aijun, Shen, Han, Li, Yang, Liu, Yong, Wu, Chao, Huang, Rui, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Association. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330586/
https://www.ncbi.nlm.nih.gov/pubmed/32622905
http://dx.doi.org/10.1016/j.jinf.2020.06.076
Descripción
Sumario:We followed–up a mild COVID-19 patient for 91 days and serially monitored his serum antibodies to four SARS-CoV-2 related antigens (NP, RBD, S1 and ECD) and neutralization activities. Our data revealed a profile of serial antibody responses during the progress and a quick decline of neutralization activities after discharge.