Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient

We followed–up a mild COVID-19 patient for 91 days and serially monitored his serum antibodies to four SARS-CoV-2 related antigens (NP, RBD, S1 and ECD) and neutralization activities. Our data revealed a profile of serial antibody responses during the progress and a quick decline of neutralization a...

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Detalles Bibliográficos
Autores principales: Yin, Shengxia, Tong, Xin, Huang, Aijun, Shen, Han, Li, Yang, Liu, Yong, Wu, Chao, Huang, Rui, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Association. Published by Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330586/
https://www.ncbi.nlm.nih.gov/pubmed/32622905
http://dx.doi.org/10.1016/j.jinf.2020.06.076
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author Yin, Shengxia
Tong, Xin
Huang, Aijun
Shen, Han
Li, Yang
Liu, Yong
Wu, Chao
Huang, Rui
Chen, Yuxin
author_facet Yin, Shengxia
Tong, Xin
Huang, Aijun
Shen, Han
Li, Yang
Liu, Yong
Wu, Chao
Huang, Rui
Chen, Yuxin
author_sort Yin, Shengxia
collection PubMed
description We followed–up a mild COVID-19 patient for 91 days and serially monitored his serum antibodies to four SARS-CoV-2 related antigens (NP, RBD, S1 and ECD) and neutralization activities. Our data revealed a profile of serial antibody responses during the progress and a quick decline of neutralization activities after discharge.
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spelling pubmed-73305862020-07-02 Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient Yin, Shengxia Tong, Xin Huang, Aijun Shen, Han Li, Yang Liu, Yong Wu, Chao Huang, Rui Chen, Yuxin J Infect Article We followed–up a mild COVID-19 patient for 91 days and serially monitored his serum antibodies to four SARS-CoV-2 related antigens (NP, RBD, S1 and ECD) and neutralization activities. Our data revealed a profile of serial antibody responses during the progress and a quick decline of neutralization activities after discharge. The British Infection Association. Published by Elsevier Ltd. 2020-09 2020-07-02 /pmc/articles/PMC7330586/ /pubmed/32622905 http://dx.doi.org/10.1016/j.jinf.2020.06.076 Text en © 2020 The British Infection Association. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Yin, Shengxia
Tong, Xin
Huang, Aijun
Shen, Han
Li, Yang
Liu, Yong
Wu, Chao
Huang, Rui
Chen, Yuxin
Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient
title Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient
title_full Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient
title_fullStr Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient
title_full_unstemmed Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient
title_short Longitudinal anti-SARS-CoV-2 antibody profile and neutralization activity of a COVID-19 patient
title_sort longitudinal anti-sars-cov-2 antibody profile and neutralization activity of a covid-19 patient
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330586/
https://www.ncbi.nlm.nih.gov/pubmed/32622905
http://dx.doi.org/10.1016/j.jinf.2020.06.076
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