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Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium
Asbestos is still a social burden worldwide as a carcinogen causing malignant mesothelioma. Whereas recent studies suggest that local iron reduction is a preventive strategy against carcinogenesis, little is known regarding the cellular and molecular mechanisms surrounding excess iron. Here by diffe...
Autores principales: | Ito, Fumiya, Yanatori, Izumi, Maeda, Yuki, Nimura, Kenta, Ito, Satoki, Hirayama, Tasuku, Nagasawa, Hideko, Kohyama, Norihiko, Okazaki, Yasumasa, Akatsuka, Shinya, Toyokuni, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330611/ https://www.ncbi.nlm.nih.gov/pubmed/32863225 http://dx.doi.org/10.1016/j.redox.2020.101616 |
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