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Overexpression of 14-3-3σ Modulates Cholangiocarcinoma Cell Survival by PI3K/Akt Signaling

The protein 14-3-3σ is involved in numerous cellular processes through its ability to bind phosphorylated serine/threonine residues. It is a key regulator of the cell cycle involving in G2 arrest by p53. Deregulation of 14-3-3σ expression has been associated with a large variety of human cancers. Ho...

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Detalles Bibliográficos
Autores principales: Wu, Qiao, Fan, Hua, Lang, Ren, Li, Xianliang, Zhang, Xingmao, Lv, Shaocheng, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330627/
https://www.ncbi.nlm.nih.gov/pubmed/32685476
http://dx.doi.org/10.1155/2020/3740418