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Metformin ameliorates bile duct ligation-induced acute hepatic injury via regulation of ER stress

Cholestasis is a condition in which the bile duct becomes narrowed or clogged by a variety of factors and bile acid is not released smoothly. Bile acid-induced liver injury is facilitated by necrotic cell death, neutrophil infiltration, and inflammation. Metformin, the first-line treatment for type...

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Detalles Bibliográficos
Autores principales: Lee, Chi-Ho, Han, Jung-Hwa, Kim, Sujin, Lee, Heejung, Kim, Suji, Nam, Dae-Hwan, Cho, Du-Hyong, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330811/
https://www.ncbi.nlm.nih.gov/pubmed/31791444
http://dx.doi.org/10.5483/BMBRep.2020.53.6.169