KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling

Introduction: Colorectal cancer (CRC) frequently harbors KRAS mutations that result in chemoresistance and metastasis. MicroRNAs (miRNAs) are usually dysregulated and play important regulatory roles in tumor progression. However, the KRAS mutation-responsive miRNA profile in CRC remains uninvestigat...

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Detalles Bibliográficos
Autores principales: Du, Feng, Cao, Tianyu, Xie, Huahong, Li, Ting, Sun, Lina, Liu, Hao, Guo, Hao, Wang, Xin, Liu, Qi, Kim, Taewan, Franklin, Jeffrey L, Graves-Deal, Ramona, Han, Weili, Tian, Zuhong, Ge, Minghui, Nie, Yongzhan, Fan, Daiming, Coffey, Robert J, Lu, Yuanyuan, Zhao, Xiaodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330859/
https://www.ncbi.nlm.nih.gov/pubmed/32641995
http://dx.doi.org/10.7150/thno.45971

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