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Nonadherent culture method promotes MSC-mediated vascularization in myocardial infarction via miR-519d/VEGFA pathway

BACKGROUND: Mesenchymal stem cells (MSCs) can provide therapeutic benefits for myocardial infarction (MI) recovery; however, the molecular mechanism by which MSCs improve the heart function is unclear. METHODS: Microarray analysis was performed to examine the expression profiling of human MSCs (hMSC...

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Detalles Bibliográficos
Autores principales: Deng, Baoping, Zhang, Xianlan, Liang, Yi, Jiang, Haiming, Huang, Weizhao, Wu, Yinmeng, Deng, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330937/
https://www.ncbi.nlm.nih.gov/pubmed/32616068
http://dx.doi.org/10.1186/s13287-020-01780-x