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Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature
BACKGROUND: Due to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma. CASE PRESENTATION: Here, we report the case of a 75-year-old Japanese man with giant paratesticular liposarcoma....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330966/ https://www.ncbi.nlm.nih.gov/pubmed/32611426 http://dx.doi.org/10.1186/s13256-020-02420-x |
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author | Noguchi, Takuro Fukushima, Toshirou Hara, Hiroaki Sekiguchi, Nodoka Kobayashi, Takashi Ozawa, Takesumi Gomi, Daisuke Koizumi, Tomonobu |
author_facet | Noguchi, Takuro Fukushima, Toshirou Hara, Hiroaki Sekiguchi, Nodoka Kobayashi, Takashi Ozawa, Takesumi Gomi, Daisuke Koizumi, Tomonobu |
author_sort | Noguchi, Takuro |
collection | PubMed |
description | BACKGROUND: Due to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma. CASE PRESENTATION: Here, we report the case of a 75-year-old Japanese man with giant paratesticular liposarcoma. Imaging studies revealed a 26 cm tumor in his right scrotum and lung metastases at presentation. He underwent radical orchiectomy followed by systemic chemotherapies. Pathological findings of the resected primary tumor confirmed a dedifferentiated liposarcoma. He then started chemotherapy treatment with gemcitabine plus docetaxel. His disease status was stable for 1 year. Eribulin was used for second-line chemotherapy. He had a relapse at 5 months after eliburin and died at 22 months after diagnosis. CONCLUSION: Early diagnosis and curative radical surgery are important for treatment of paratesticular liposarcoma. However, a giant paratesticular liposarcoma could cause metastases, and systemic chemotherapy may be helpful for prolonging survival in patients with metastatic paratesticular liposarcoma. |
format | Online Article Text |
id | pubmed-7330966 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-73309662020-07-02 Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature Noguchi, Takuro Fukushima, Toshirou Hara, Hiroaki Sekiguchi, Nodoka Kobayashi, Takashi Ozawa, Takesumi Gomi, Daisuke Koizumi, Tomonobu J Med Case Rep Case Report BACKGROUND: Due to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma. CASE PRESENTATION: Here, we report the case of a 75-year-old Japanese man with giant paratesticular liposarcoma. Imaging studies revealed a 26 cm tumor in his right scrotum and lung metastases at presentation. He underwent radical orchiectomy followed by systemic chemotherapies. Pathological findings of the resected primary tumor confirmed a dedifferentiated liposarcoma. He then started chemotherapy treatment with gemcitabine plus docetaxel. His disease status was stable for 1 year. Eribulin was used for second-line chemotherapy. He had a relapse at 5 months after eliburin and died at 22 months after diagnosis. CONCLUSION: Early diagnosis and curative radical surgery are important for treatment of paratesticular liposarcoma. However, a giant paratesticular liposarcoma could cause metastases, and systemic chemotherapy may be helpful for prolonging survival in patients with metastatic paratesticular liposarcoma. BioMed Central 2020-07-02 /pmc/articles/PMC7330966/ /pubmed/32611426 http://dx.doi.org/10.1186/s13256-020-02420-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Noguchi, Takuro Fukushima, Toshirou Hara, Hiroaki Sekiguchi, Nodoka Kobayashi, Takashi Ozawa, Takesumi Gomi, Daisuke Koizumi, Tomonobu Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature |
title | Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature |
title_full | Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature |
title_fullStr | Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature |
title_full_unstemmed | Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature |
title_short | Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature |
title_sort | giant paratesticular liposarcoma with lung metastases: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330966/ https://www.ncbi.nlm.nih.gov/pubmed/32611426 http://dx.doi.org/10.1186/s13256-020-02420-x |
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