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Proteus: An algorithm for proposing stabilizing mutation pairs based on interactions observed in known protein 3D structures
BACKGROUND: Protein engineering has many applications for industry, such as the development of new drugs, vaccines, treatment therapies, food, and biofuel production. A common way to engineer a protein is to perform mutations in functionally essential residues to optimize their function. However, th...
Autores principales: | Barroso, José Renato M. S., Mariano, Diego, Dias, Sandro R., Rocha, Rafael E. O., Santos, Lucianna H., Nagem, Ronaldo A. P., de Melo-Minardi, Raquel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330979/ https://www.ncbi.nlm.nih.gov/pubmed/32611389 http://dx.doi.org/10.1186/s12859-020-03575-6 |
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